Orange Peel (Citrus sinensis) C/S Organic Potential Health Benefits Orange peel is rich in nutrients and bioactive compounds that may offer various health benefits:

•  Rich in Nutrients: Contains high levels of vitamin C, fiber, provitamin A, folate,

and calcium. Just one tablespoon (6 grams) of orange peel provides about 14% of the Daily Value for vitamin C and four times more fiber than the fruit itself.

•  Antioxidant and Anti-inflammatory Properties: Packed with polyphenols like

hesperidin and polymethoxyflavones (PMFs), which have been studied for their potential to reduce inflammation and oxidative stress. 

•  Heart Health: Animal studies suggest that orange peel extract may help improve

cardiovascular health by influencing gut microbiota and reducing levels of trimethylamine N-oxide (TMAO), a compound linked to heart disease. 

•  Digestive Aid: Traditionally used to alleviate indigestion, bloating, and gas due

to its carminative properties.

•  Skin Health: The antioxidants in orange peel may help improve skin tone and

reduce signs of aging by combating free radicals.   Recommended Daily Dosage While there is no standardized dosage for orange peel, general guidelines include:

•  Dried Orange Peel Tea: Steep 1–2 teaspoons of dried orange peel in hot water

for 10–15 minutes. Consume up to three times daily.

•  Powdered Orange Peel: Typically taken in doses of 500–1,000 mg, one to three

times daily.

•  Tincture: Follow the manufacturer's instructions, usually around 1–2 mL, taken

two to three times daily. Note: It's essential to consult with a healthcare provider before starting any new supplement regimen, especially for prolonged use.

 Interactions with Medications Orange peel may interact with certain medications:

•  Celiprolol (Celicard): Consuming large amounts of sweet orange juice might

decrease how much celiprolol the body absorbs, potentially reducing its effectiveness. 

•  Ivermectin (Stromectol): Orange juice might increase the absorption of

ivermectin, leading to higher levels in the body. 

•  General Medication Interactions: Compounds in orange peel can inhibit certain

enzymes and transporters (like CYP3A4 and P-glycoprotein), potentially affecting the metabolism of various drugs.  Contraindications:

•  Pregnancy and Breastfeeding: Due to insufficient safety data, it's

recommended to avoid medicinal amounts of orange peel during pregnancy and lactation. 

•  Children: Large amounts of sweet orange peel are possibly unsafe for children

and can cause adverse effects.