Orange Peel (Citrus sinensis) C/S Organic
Potential Health Benefits
Orange peel is rich in nutrients and bioactive compounds that may offer various health
benefits:
 
 Rich in Nutrients: Contains high levels of vitamin C, fiber, provitamin A, folate,
and calcium. Just one tablespoon (6 grams) of orange peel provides about 14%
of the Daily Value for vitamin C and four times more fiber than the fruit itself
. Healthline
 Antioxidant and Anti-inflammatory Properties: Packed with polyphenols like
hesperidin and polymethoxyflavones (PMFs), which have been studied for their
potential to reduce inflammation and oxidative stress. Healthline
 Heart Health: Animal studies suggest that orange peel extract may help improve
cardiovascular health by influencing gut microbiota and reducing levels of
trimethylamine N-oxide (TMAO), a compound linked to heart disease. Medical
News Today
 Digestive Aid: Traditionally used to alleviate indigestion, bloating, and gas due
to its carminative properties.
 Skin Health: The antioxidants in orange peel may help improve skin tone and
reduce signs of aging by combating free radicals. MedicineNet
 Recommended Daily Dosage
While there is no standardized dosage for orange peel, general guidelines include:
 Dried Orange Peel Tea: Steep 1–2 teaspoons of dried orange peel in hot water
for 10–15 minutes. Consume up to three times daily.
 Powdered Orange Peel: Typically taken in doses of 500–1,000 mg, one to three
times daily.
 Tincture: Follow the manufacturer's instructions, usually around 1–2 mL, taken
two to three times daily.
Note: It's essential to consult with a healthcare provider before starting any new
supplement regimen, especially for prolonged use.

 Interactions with Medications
Orange peel may interact with certain medications:
 
 
 Celiprolol (Celicard): Consuming large amounts of sweet orange juice might
decrease how much celiprolol the body absorbs, potentially reducing its
effectiveness. WebMD
 Ivermectin (Stromectol): Orange juice might increase the absorption of
ivermectin, leading to higher levels in the body. RxList
 General Medication Interactions: Compounds in orange peel can inhibit certain
enzymes and transporters (like CYP3A4 and P-glycoprotein), potentially affecting
the metabolism of various drugs. IJCRT
Contraindications:
 Pregnancy and Breastfeeding: Due to insufficient safety data, it's
recommended to avoid medicinal amounts of orange peel during pregnancy and
lactation. WebMD
 Children: Large amounts of sweet orange peel are possibly unsafe for children
and can cause adverse effects. WebMD